Entertainment, in all of its varied forms, has long enthralled human minds – stirring emotions, encouraging creativity, providing moments of sheer delight and introspection. Recently however, more attention has been drawn to the intersection between entertainment and brain science; showing us the myriad responses our brains make when watching movies, music videos or playing video games; this combination of arts and neuroscience not only deepens understanding about human cognition, but can lead to innovative therapies or transformative experiences as well. 1. Neurochemical Pleasures: An Overview The Neurochemical Pleasures: Entertainment begins in our brain’s pleasure centers. Engaging with enjoyable content triggers…